Sirijan Santajit
Faculty of Tropical Medicine, Mahidol University, BKK 10400, Thailand
Biography
Ms. Sirijan Santajit is a Ph.D. (Tropical Medicine) candidate in Mahidol University and my ongoing research project is about the production of human monoclonal single-chain variable fragments (HuscFvs) that can neutralize the biological activities of Exotoxin A and interfering quorum sensing signals in Pseudomonas aeruginosa using phage display technology and the computerized simulation to predict insight into the mechanism of the antibodies render bacterial virulence factors neutralization. In the future, I would like to discovery of the therapeutic proteins and phage display-based therapeutic antibody against virulence determinants of their organisms in order to help patients who suffered from infectious diseases.
Abstract
Abstract : Human Single-Chain Antibodies to ETA: Potential Therapeutic Agent against Pseudomonal Infection