Antibiotic Challenges in Pediatric and Geriatric Populations

Antibiotic challenges in pediatric and geriatric populations arise due to unique physiological and metabolic differences. In children, immature organ systems affect drug absorption, distribution, metabolism, and excretion, increasing the risk of underdosing or toxicity. Geriatric patients often have multiple comorbidities and altered pharmacokinetics, leading to increased sensitivity and drug interactions. Both groups are vulnerable to antibiotic resistance due to frequent infections and prolonged treatments. Careful dose adjustment, monitoring, and selecting appropriate antibiotics are essential to optimize therapeutic outcomes and minimize adverse effects. Addressing these challenges is critical for effective infection management and improving patient safety across these age groups.

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